Education:
University of Notre Dame
Biochemistry and Theology majors
B.A./B.S., 2018
University of Minnesota
Biochemistry, Molecular Biology and Biophysics Graduate Program
Ph.D., 2024
MSTP Governance:
- Student Admissions and Recruitment Committee, 2020-2023 (co-chair 2021-2023)
- Student Advisory Committee, 2024-2025
Thesis Advisor: Wendy Gordon, Ph.D.
Thesis Research
Effect of Alzheimer disease mutations on APP cleavage.
Publications (pubmed)
Anderson MJM, Hayward AN, Smiley AT, Shi K, Pawlak MR, Aird EJ, Grant E, Greenberg L, Aihara H, Evans RL 3rd, Ulens C, Gordon WR. Molecular basis of proteolytic cleavage regulation by the extracellular matrix receptor dystroglycan. Structure. 2024 Nov 7;32(11):1984-1996.e5.
Lemmex ACD, Allred J, Ostergard J, Trask J, Bui HN, Anderson MJM, Kopp B, Streeter O, Smiley AT, Babilonia-Díaz NS, Blazar BR, Higgins L, Gordon PM, Muretta JM, Gordon WR. Single-chain nanobody inhibition of Notch and avidity enhancement utilizing the β-pore forming toxin Aerolysin. bioRxiv [Preprint]. 2024 Oct 25:2024.10.22.617501. PMCID: PMC11526928
Smiley AT, Babilonia-Díaz NS, Hughes AJ, Lemmex ACD, Anderson MJM, Tompkins KJ, Gordon WR. HUHgle: An Interactive Substrate Design Tool for Covalent Protein-ssDNA Labeling Using HUH-Tags. ACS Synth Biol. 2024 Jun 21;13(6):1669-1678.
Ramirez MP, Anderson MJM, Kelly MD, Sundby LJ, Hagerty AR, Wenthe SJ, Odde DJ, Ervasti JM, Gordon WR. Dystrophin missense mutations alter focal adhesion tension and mechanotransduction. Proc Natl Acad Sci USA. 2022 Jun 21;119(25):e2205536119. PMCID: PMC10713350
Work prior to the UMN MSTP:
Riley TP, Ayres CM, Hellman LM, Singh NK, Cosiano M, Cimons JM, Anderson MJ, Piepenbrink KH, Pierce BG, Weng Z, Baker BM. A generalized framework for computational design and mutational scanning of T-cell receptor binding interfaces. Protein Eng Des Sel. 2016 Dec;29(12):595-606. PMCID: PMC5181382
