Education:
University of Massachusetts - Boston
Biochemistry major, Creative Writing minor
B.S., 2020
MSTP Student Governance:
- Student Admissions and Recruitment Committee, 2024-2025
- Student Advisory Committee, 2025-2026
Thesis Advisors: David Ferguson, Ph.D and Anthony Baughn, Ph.D.
Publications
Liu Q, Wallach JB, Jayasinghe YP, Sullivan MR, Proietto J, Rodriguez S, Vo S, Boshoff HIM, Jia Z, Ostrer L, Mehdiratta K, Shi R, Dartois V, Baughn AD, Rubin EJ, Ronning DR, Zimmerman MD, Schnappinger D, Aldrich CC. Structure-Guided Development of a Potent BioA Inhibitor Validates Biotin Synthesis Inhibition as a Therapeutic Strategy for Tuberculosis. bioRxiv [Preprint]. 2025 Sep 24:2025.09.24.678246. doi: 10.1101/2025.09.24.678246. PMCID: PMC12485673
Ostrer L, Crooks TA, Howe MD, Vo S, Jia Z, Hegde P, Schacht N, Aldrich CC, Baughn AD. Mechanism of the dual action self-potentiating antitubercular drug morphazinamide. PNAS Nexus. 2025 Jul 29;4(8):pgaf242. PMCID: PMC12342587
Ostrer L, Crooks TA, Howe MD, Vo S, Jia Z, Hegde P, Schacht N, Aldrich CC, Baughn AD. Mechanism of the Dual Action Self-Potentiating Antitubercular Drug Morphazinamide. bioRxiv [Preprint]. 2025 Jan 31:2024.10.08.617272. Update in: PNAS Nexus. 2025 Jul 29;4(8):pgaf242. PMCID: PMC11482805
For work prior to the UMN MSTP:
Zephyr J, Nageswara Rao D, Vo SV, Henes M, Kosovrasti K, Matthew AN, Hedger AK, Timm J, Chan ET, Ali A, Kurt Yilmaz N, Schiffer CA. Deciphering the Molecular Mechanism of HCV Protease Inhibitor Fluorination as a General Approach to Avoid Drug Resistance. 2022. Journal of molecular biology, 434(9), 167503.
