Michael T. Patterson

Class of
2019


Education:
Millsaps College
Biochemistry major
B.S., 2017

University of Minnesota
Microbiology, Immunology and Cancer Biology Graduate Program
Ph.D., 2024

MSTP Student Governance: 

  • Student Advisory Committee, 2023-24

Thesis advisor: Jesse Williams, Ph.D.

Thesis Research

Mechanisms of monocyte differentiation upon entry into atherosclerotic plaques.

Publications  (pubmed)

Patterson MT, Burrack AL, Xu Y, Hickok GH, Schmiechen ZC, Becker S, Cruz-Hinojoza E, Schrank PR, Kennedy AE, Firulyova MM, Miller EA, Zaitsev K, Williams JW, Stromnes IM. Tumor-specific CD4 T cells instruct monocyte fate in pancreatic ductal adenocarcinoma. Cell Rep. 2023 Jul 25;42(7):112732. PMCID: PMC10448358 

Zhang N, Harsch B, Zhang MJ, Gyberg DJ, Stevens JA, Wagner BM, Mendelson J, Patterson MT, Orchard DA, Healy CL, Williams JW, Townsend D, Shearer GC, Murphy KA, O'Connell TD. FFAR4 regulates cardiac oxylipin balance to promote inflammation resolution in HFpEF secondary to metabolic syndrome. J Lipid Res. 2023 Jun;64(6):100374. PMCID: PMC10209340

Burrack AL, Schmiechen ZC, Patterson MT, Miller EA, Spartz EJ, Rollins MR, Raynor JF, Mitchell JS, Kaisho T, Fife BT, Stromnes IM. Distinct myeloid antigen-presenting cells dictate differential fates of tumor-specific CD8+ T cells in pancreatic cancer. JCI Insight. 2022 Apr 8;7(7):e151593. PMCID: PMC9057584

Patterson MT, Williams JW. Metabolic regulation of macrophage proliferation and function in atherosclerosis. 2021 Oct 1;32(5):293-300. Review. PMCID: PMC8416794

Work prior to UMN MSTP:

Wachsmuth LP, Patterson MT, Eckhaus MA, Venzon DJ, Kanakry CG. Optimized Timing of Post-Transplantation Cyclophosphamide in MHC-Haploidentical Murine Hematopoietic Cell Transplantation. Biol Blood Marrow Transplant. 2020 Feb;26(2):230-241.

Bendel RE, Patterson MT. Long-term Effectiveness of Trabectome (Ab-interno Trabeculectomy) Surgery. J Curr Glaucoma Pract. 2018 Sep-Dec;12(3):119-124. PMCID: PMC6647824

Wachsmuth LP, Patterson MT, Eckhaus MA, Venzon DJ, Gress RE, Kanakry CG. Post-transplantation cyclophosphamide prevents graft-versus-host disease by inducing alloreactive T cell dysfunction and suppression. J Clin Invest. 2019 Mar 26;129(6):2357-2373. PMCID: PMC6546453

Michael T.