Michael T. Patterson

Publications  (pubmed)

Kazmirczak F, Vogel NT, Prisco SZ, Patterson MT, Annis J, Moon RT, Hartweck LM, Mendelson JB, Kim M, Calixto Mancipe N, Markowski T, Higgins L, Guerrero C, Kremer B, Blake ML, Rhodes CJ, Williams JW, Brittain EL, Prins KW. Ferroptosis-Mediated Inflammation Promotes Pulmonary Hypertension. Circ Res. 2024 Nov 8;135(11):1067-1083. 

Kazmirczak F, Vogel NT, Prisco SZ, Patterson MT, Annis J, Moon RT, Hartweck LM, Mendelson JB, Kim M, Mancipe NC, Markowski T, Higgins L, Guerrero C, Kremer B, Blake ML, Rhodes CJ, Williams JW, Brittain EL, Prins KW. Ferroptosis Integrates Mitochondrial Derangements and Pathological Inflammation to Promote Pulmonary Hypertension. bioRxiv [Preprint]. 2024 Sep 23:2023.01.19.524721. 

Patterson MT, Prins KW. An exercise in relaxation: right ventricular diastolic function predicts exercise capacity in pulmonary arterial hypertension. Eur Respir J. 2024 Jul 18;64(1):2401142. 

Patterson MT, Xu Y, Hillman H, Osinski V, Schrank PR, Kennedy AE, Barrow F, Zhu A, Tollison S, Shekhar S, Stromnes IM, Tassi I, Wu D, Revelo XS, Binstadt BA, Williams JW. Trem2 Agonist Reprograms Foamy Macrophages to Promote Atherosclerotic Plaque Stability-Brief Report. Arterioscler Thromb Vasc Biol. 2024 Jul;44(7):1646-1657. PMCID: PMC11208052

Patterson MT, Prins KW. Noninvasive assessment of liver stiffness in right heart failure: A new phenotype requiring further exploration. J Heart Lung Transplant. 2024 Jul;43(7):1116-1117. 

Xu Y, Patterson MT, Dolfi B, Zhu A, Bertola A, Schrank PR, Gallerand A, Kennedy AE, Hillman H, Dinh L, Shekhar S, Tollison S, Bold TD, Ivanov S, Williams JW. Adrenal gland macrophages regulate glucocorticoid production through Trem2 and TGFβ. JCI Insight. 2024 Jun 13:e174746.

Patterson MT, Firulyova MM, Xu Y, Hillman H, Bishop C, Zhu A, Hickok GH, Schrank PR, Ronayne CE, Caillot Z, Fredrickson G, Kennedy AE, Acharya N, Neels JG, Chinetti G, Revelo X, Stromnes IM, Ivanov S, Bold TD, Zaitsev K, Williams JW. Trem2 promotes foamy macrophage lipid uptake and survival in atherosclerosis. Nat Cardiovasc Res. 2023 Nov;2(11):1015-1031. PMCID: PMC11031198

Patterson MT, Burrack AL, Xu Y, Hickok GH, Schmiechen ZC, Becker S, Cruz-Hinojoza E, Schrank PR, Kennedy AE, Firulyova MM, Miller EA, Zaitsev K, Williams JW, Stromnes IM. Tumor-specific CD4 T cells instruct monocyte fate in pancreatic ductal adenocarcinoma. Cell Rep. 2023 Jul 25;42(7):112732. PMCID: PMC10448358 

Zhang N, Harsch B, Zhang MJ, Gyberg DJ, Stevens JA, Wagner BM, Mendelson J, Patterson MT, Orchard DA, Healy CL, Williams JW, Townsend D, Shearer GC, Murphy KA, O'Connell TD. FFAR4 regulates cardiac oxylipin balance to promote inflammation resolution in HFpEF secondary to metabolic syndrome. J Lipid Res. 2023 Jun;64(6):100374. PMCID: PMC10209340

Burrack AL, Schmiechen ZC, Patterson MT, Miller EA, Spartz EJ, Rollins MR, Raynor JF, Mitchell JS, Kaisho T, Fife BT, Stromnes IM. Distinct myeloid antigen-presenting cells dictate differential fates of tumor-specific CD8+ T cells in pancreatic cancer. JCI Insight. 2022 Apr 8;7(7):e151593. PMCID: PMC9057584

Patterson MT, Williams JW. Metabolic regulation of macrophage proliferation and function in atherosclerosis. 2021 Oct 1;32(5):293-300. Review. PMCID: PMC8416794

Work prior to UMN MSTP:

Wachsmuth LP, Patterson MT, Eckhaus MA, Venzon DJ, Kanakry CG. Optimized Timing of Post-Transplantation Cyclophosphamide in MHC-Haploidentical Murine Hematopoietic Cell Transplantation. Biol Blood Marrow Transplant. 2020 Feb;26(2):230-241.

Bendel RE, Patterson MT. Long-term Effectiveness of Trabectome (Ab-interno Trabeculectomy) Surgery. J Curr Glaucoma Pract. 2018 Sep-Dec;12(3):119-124. PMCID: PMC6647824

Wachsmuth LP, Patterson MT, Eckhaus MA, Venzon DJ, Gress RE, Kanakry CG. Post-transplantation cyclophosphamide prevents graft-versus-host disease by inducing alloreactive T cell dysfunction and suppression. J Clin Invest. 2019 Mar 26;129(6):2357-2373. PMCID: PMC6546453